Immunoexpression of transforming growth factor beta and interferon gamma in radicular and dentigerous cysts

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dc.contributor.authorMoraes, Maiara de
dc.contributor.authorRocha-Neto, Pedro Carlos da
dc.contributor.authorMatos, Felipe Rodrigues de
dc.contributor.authorLopes, Maria Luiza Diniz de Sousa
dc.contributor.authorAzevedo, Paulo Roberto Medeiros de
dc.contributor.authorCosta, Antonio de Lisboa Lopes
dc.date.accessioned2023-03-24T19:20:07Z
dc.date.available2023-03-24T19:20:07Z
dc.date.issued2014-09
dc.description.resumoIntroduction: The aim of this study was to evaluate and compare the immunohistochemical expression of transforming growing factor beta (TGF-b) and interferon gamma (IFN-g) between radicular cysts (RCs) and dentigerous cysts (DCs). Methods: Twenty RCs and DCs were selected for analysis of the immunoexpression of TGF-b and IFN-g in the epithelium and capsule. Results: The cell reactivity of TGF-b and IFN-g in the lining epithelium and capsule of RCs showed no significant differences when compared with DCs (P > .05). There was a tendency of a higher expression of TGF-b in the capsule of DCs. Conclusions: Our results showed the presence of TGF-b and IFN-g in RCs and DCs, supporting the hypothesis that both participate in the development of these lesions, where IFN-g usually plays a role in bone resorption, which is counterbalanced by the osteoprotective activity performed by TGF-b.pt_BR
dc.identifier.citationMORAES, Maiara de. et al. Immunoexpression of transforming growth factor beta and Interferon gamma in radicular and dentigerous cysts. Journal of Endodontics, v. 40, p. 1293-1297, 2014. Disponível em: http://www.sciencedirect.com/science/article/pii/S0099239914000697. Acesso em: 08 dez. 2017.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.joen.2014.01.010
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/51950
dc.languageenpt_BR
dc.publisherElsevierpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectDentigerous cystpt_BR
dc.subjectImmunohistochemistrypt_BR
dc.subjectInterferon gammapt_BR
dc.subjectRadicular cystpt_BR
dc.subjectTransforming growth factorspt_BR
dc.titleImmunoexpression of transforming growth factor beta and interferon gamma in radicular and dentigerous cystspt_BR
dc.typearticlept_BR

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