Adenomatoid odontogenic tumor: retrospective study of 15 cases with emphasis on histopathologic features

dc.contributor.authorMatos, Felipe Rodrigues de
dc.contributor.authorNonaka, Cassiano Francisco Weege
dc.contributor.authorPinto, Leão Pereira
dc.contributor.authorSouza, Lelia Batista de
dc.contributor.authorFreitas, Roseana de Almeida
dc.date.accessioned2017-01-30T14:03:32Z
dc.date.available2017-01-30T14:03:32Z
dc.date.issued2012
dc.description.resumoAdenomatoid odontogenic tumor (AOT) is an uncommon benign epithelial lesion of odontogenic origin and, thus far, only few studies regarding the frequency of its many histopathologic features have been published in the literature. Thus, the aim of this study was to perform a retrospective analysis in a case series of AOT, with emphasis on the histopathological features. Fifteen cases of AOT were studied considering their clinical, radiographic and histopathologic aspects. Twelve cases affected females and the mean age was 16.2 years. The anterior maxilla was the most common site (66.6 %) and radiographically most cases showed a unilocular radiolucency with well-defined borders (57.1 %). Histologically, most cases exhibited predominantly a solid growth pattern (46.7 %) or a similar proportion of solid and cribriform patterns (46.7 %). Eosinophilic amorphous material ("tumor droplets") was found in all cases (100 %). Most tumors showed duct-like spaces (93.3 %) and convoluted structures (60.0 %) whereas a minor proportion of cases presented calcifying epithelial odontogenic tumor (CEOT)-like areas (26.7 %). Variable amounts of calcified material were found in most AOTs (80.0 %) whereas osteodentin and perivascular hyalinization were seen only rarely (6.7 % each one). Five (33.3 %) cases had areas mimicking a dentigerous cyst and most of these were diagnosed in females (80.0 %). Regarding the histopathologic features, our results suggest that AOTs usually show predominance of solid pattern or a similar proportion of solid and cribriform patterns while osteodentin and perivascular hyalinization are rarely seen in these tumors. In addition, areas mimicking a dentigerous cyst and CEOT-like areas are relatively infrequent findings in AOTs.pt_BR
dc.identifier.citationMATOS, Felipe Rodrigues de et al. Adenomatoid Odontogenic Tumor: Retrospective Study of 15 Cases with Emphasis on Histopathologic Features. Head and Neck Pathology, v. 6, n. 4, p. 430-437, 2012.pt_BR
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/21809
dc.languageengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAdenomatoid odontogenic tumorpt_BR
dc.subjectOdontogenic tumorpt_BR
dc.subjectClinicalpt_BR
dc.subjectHistopathologypt_BR
dc.titleAdenomatoid odontogenic tumor: retrospective study of 15 cases with emphasis on histopathologic featurespt_BR
dc.typearticlept_BR

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