Incorporation and remodeling of bone block allografts in the maxillary reconstruction: a randomized clinical trial

dc.contributor.authorDeluiz, Daniel
dc.contributor.authorOliveira, Luciano Santos
dc.contributor.authorPires, Fábio Ramôa
dc.contributor.authorReiner, Teresita
dc.contributor.authorArmada, Luciana
dc.contributor.authorNunes, Marcus A.
dc.contributor.authorTinoco, Eduardo Muniz Barretto
dc.date.accessioned2022-12-08T20:58:21Z
dc.date.available2022-12-08T20:58:21Z
dc.date.issued2016
dc.description.resumoBackground: Severe alveolar atrophy often presents a challenge for the implant surgery. The significant lack of bone in the alveolar ridges may compromise the final restorations both from the aesthetic and functional standpoints. Objectives: To evaluate the behavior of bone block allografts for the maxillary augmentation and to investigate its incorporation, remodeling, and implant survival rates in two different healing time points. Material and Methods: Sixty-six consecutive patients (52 female/14 male, mean age: 57.9569.06 years old), presenting 113 atrophic alveolar ridges underwent maxillary augmentation with fresh-frozen allogeneic bone blocks from tibia. Patients were randomly assigned in two groups: Group 1—patients who would wait 4 months for implant placement after grafting, and Group 2—patients who would wait 6 months. Events of infection, suture dehiscence or mucosal perforation were recorded. Cone-beam computed tomography scans were compared volumetrically between the time of the grafting surgery and reentry procedure after incorporation. Biopsies were collected and subjected to histological, histomorphometric and immunehistochemical analysis. Results: A total of 305 implants were placed in the reconstructed sites. The mean resorption rate in Group 1 (13.98%65.59) was significantly lower than Group 2 (31.52%66.31). The amount of calcified tissue, newly formed bone and remaining graft particles demonstrated no difference between groups. The samples showed evident immunolabeling for the podoplanin protein in both groups. The implants cumulative survival rate was 94.76%. Conclusions: The findings of the present study indicate that there is a significant difference regarding the resorption of the grafts when waiting 4 or 6 months before placing the implants, even though no difference was found in the histological, histomorphometric, and immunohistochemical features. Both 4-month and 6-months healing times are suitable for the implant placement.pt_BR
dc.identifier.citationDELUIZ, Daniel; et al.Incorporation and remodeling of bone block allografts in the maxillary reconstruction: a randomized clinical trial. Clinical Implant Dentistry and Related Research , v. 19, p. 180-194, 2016. Disponível em: http://onlinelibrary.wiley.com/doi/10.1111/cid.12441/abstract . Acesso em: 07 dez. 2017pt_BR
dc.identifier.doihttps://doi.org/10.1111/cid.12441
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/50050
dc.languageenpt_BR
dc.publisherWileypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectAlveolar ridge reconstruction,pt_BR
dc.subjectBone allograftpt_BR
dc.subjectBone augmentationpt_BR
dc.subjectBone graftingpt_BR
dc.subjectEdentulous atrophic maxillapt_BR
dc.subjectImplant survivalpt_BR
dc.subjectRandomized controlled trialpt_BR
dc.subjectHistological analysispt_BR
dc.titleIncorporation and remodeling of bone block allografts in the maxillary reconstruction: a randomized clinical trialpt_BR
dc.typearticlept_BR

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