Morphological changes in the suprachiasmatic nucleus of aging female marmosets (callithrix jacchus)

dc.contributor.authorEngelberth, Rovena Clara G. J.
dc.contributor.authorSilva, Kayo Diogenes de A.
dc.contributor.authorAzevedo, Carolina V. de M.
dc.contributor.authorGavioli, Elaine Cristina
dc.contributor.authorSantos, Jose Ronaldo dos
dc.contributor.authorSoares, Joacil Germano
dc.contributor.authorNascimento Junior, Expedito S.
dc.contributor.authorCavalcante, Judney C.
dc.contributor.authorCosta, Miriam Stela M. O.
dc.contributor.authorCavalcante, Jeferson S.
dc.date.accessioned2018-02-05T19:41:19Z
dc.date.available2018-02-05T19:41:19Z
dc.date.issued2014
dc.description.resumoThe suprachiasmatic nuclei (SCN) are pointed to as the mammals central circadian pacemaker. Aged animals show internal time disruption possibly caused by morphological and neurochemical changes in SCN components. Some studies reported changes of neuronal cells and neuroglia in the SCN of rats and nonhuman primates during aging. The effects of senescence on morphological aspects in SCN are important for understanding some alterations in biological rhythms expression. Therefore, our aim was to perform a comparative study of the morphological aspects of SCN in adult and aged female marmoset. Morphometric analysis of SCN was performed using Nissl staining, NeuN-IR, GFAP-IR, and CB-IR. A significant decrease in the SCN cells staining with Nissl, NeuN, and CB were observed in aged female marmosets compared to adults, while a significant increase in glial cells was found in aged marmosets, thus suggesting compensatory process due to neuronal loss evoked by agingpt_BR
dc.identifier.citationENGELBERTH, Rovena Clara G. J. et al. Morphological changes in the suprachiasmatic nucleus of aging female marmosets (callithrix jacchus). BioMed Research International, p. 1-10, 2014. Disponível em <https://www.hindawi.com/journals/bmri/2014/243825/>. Acesso em: 20 nov. 2017.pt_BR
dc.identifier.doi10.1155/2014/243825
dc.identifier.issn2314-6133
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/24706
dc.languageengpt_BR
dc.publisherHindawi Publishing Corporationpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectSuprachiasmaticpt_BR
dc.subjectPacemakerpt_BR
dc.subjectNeuN-IRpt_BR
dc.titleMorphological changes in the suprachiasmatic nucleus of aging female marmosets (callithrix jacchus)pt_BR
dc.typearticlept_BR

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