Psychotropics in different causes of itch: systematic review with controlled studies

Brasileiro, Lízie Emanuelle Eulalio; Barreto, Dayanna Patrícia de Carvalho; Nunes, Emerson Arcoverde

Psychotropics in different causes of itch: systematic review with controlled studies

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dc.contributor.author	Brasileiro, Lízie Emanuelle Eulalio
dc.contributor.author	Barreto, Dayanna Patrícia de Carvalho
dc.contributor.author	Nunes, Emerson Arcoverde
dc.date.accessioned	2020-12-17T12:08:15Z
dc.date.available	2020-12-17T12:08:15Z
dc.date.issued	2016-12
dc.description.resumo	Among the wide range of symptoms neglected or resistant to conventional treatments in clinical practice, itch is emerging gradually as a theme to be studied. Itch complaints and the negative effects in the quality of life are observed in several medical fields. Although the partially obscure pathophysiology, some researchers decided to check and test the use of psychotropic drugs in resistant itch to conventional topical treatments and antihistamines. The objective of this study was to evaluate scientific evidence in psychotropic use in the treatment of itch of various causes. This is a systematic review of scientific literature. The following databases were used: PubMed, Web of Science, Scopus and Scielo. Randomized controlled trials that should focus on treatment with psychotropic drugs of pruritus of various causes were the inclusion criteria. All articles were analyzed by the authors, and the consensus was reached in cases of disagreement. Fifteen articles were included after analysis and selection in databases, with the majority of clinical trials focusing on psychopharmacological treatment of itch on account of chronic kidney disease. Clinical trials with psychotropic drugs mostly indicated significant improvement in the itching. In most trials of chronic kidney disease as basal disease for itch, greater effectiveness was observed with the use of psychotropic drugs compared with placebo or other antipruritic. However, the small amount of controlled trials conducted precludes the generalization that psychiatric drugs are effective for itch of various causes	pt_BR
dc.identifier.citation	BRASILEIRO, Lízie Emanuelle Eulalio; BARRETO, Dayanna Patrícia de Carvalho; NUNES, Emerson Arcoverde. Psychotropics in different causes of itch: systematic review with controlled studies. Anais Brasileiros de Dermatologia, [s. l.], v. 91, n. 6, p. 791-798, dez. 2016. Disponível em: https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962016000600791&lng=en&tlng=en. Acesso em: 16 out. 2020. http://dx.doi.org/10.1590/abd1806-4841.20164878	pt_BR
dc.identifier.doi	10.1590/abd1806-4841.20164878
dc.identifier.issn	0365-0596
dc.identifier.issn	1806-4841
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/31031
dc.language	en	pt_BR
dc.publisher	Sociedade Brasileira de Dermatologia	pt_BR
dc.rights	Attribution-NonCommercial 3.0 Brazil	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc/3.0/br/	*
dc.subject	Pruritus	pt_BR
dc.subject	Psychotropic drugs	pt_BR
dc.subject	Controlled clinical trial	pt_BR
dc.title	Psychotropics in different causes of itch: systematic review with controlled studies	pt_BR
dc.type	article	pt_BR