Impact of curcumin on energy metabolism in HIV infection: a case study

dc.contributor.authorMedeiros, Gidyenne Christine Bandeira Silva de
dc.contributor.authorSilva, Tatiane Andreza Lima da
dc.contributor.authorMedeiros, Radamés Maciel Vítor
dc.contributor.authorMedeiros, Danielle Coutinho de
dc.contributor.authorMedeiros, Rafaela Catherine da Silva Cunha
dc.contributor.authorMedeiros, Jason Azevedo de
dc.contributor.authorAndrade, Ricardo Dias de
dc.contributor.authorLais, Lucia Leite
dc.contributor.authorDantas, Paulo Moreira Silva
dc.date.accessioned2024-07-30T22:21:34Z
dc.date.available2024-07-30T22:21:34Z
dc.date.issued2019-01
dc.description.resumoProlonged use of antiretroviral therapy (ART) has been associated with dyslipidemia and impaired energy substrate oxidation (SOxi). Curcumin is a natural bioactive compound, which interacts with molecular targets and holds important metabolic properties. The aim of this study was to evaluate the effect of curcumin supplementation on energetic metabolism of an adult female with HIV/AIDS and under ART. The intervention was performed with 500 mg/day of curcumin for 27 days. Glycemic and lipid profile and SOxi at rest were evaluated before and after intervention. After intervention, improvement of lipid profile and insulin sensibility was observed. Moreover, there was a positive modulation of SOxi at rest. Oral curcumin supplementation can positively modulate the energy metabolism of people living with HIV/AIDS using the ART. However, clinical studies are required in order to confirm our findings in a representative samplept_BR
dc.identifier.citationSILVA, Tatiane Andreza Lima da; MEDEIROS, Radamés Maciel Vítor; MEDEIROS, Danielle Coutinho de; MEDEIROS, Rafaela Catherine da Silva Cunha; MEDEIROS, Jason Azevedo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; ANDRADE, Ricardo Dias de; LAIS, Lucia Leite; DANTAS, Paulo Moreira Silva. Impact of curcumin on energy metabolism in HIV infection: a case study. Phytotherapy Research, [S.l.], v. 33, n. 3, p. 856-858, 15 jan. 2019. DOI: 10.1002/ptr.6258. Disponível em: https://onlinelibrary.wiley.com/doi/10.1002/ptr.6258. Acesso em: 10 jul. 2024.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1002/ptr.6258
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/58907
dc.languageenpt_BR
dc.publisherPhytotherapy Researchpt_BR
dc.rightsAttribution 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/br/*
dc.subjectAcquired immunodeficiency syndromept_BR
dc.subjectAntiretroviral therapypt_BR
dc.subjectCurcuminpt_BR
dc.subjectDyslipidemiapt_BR
dc.subjectEnergy metabolismpt_BR
dc.titleImpact of curcumin on energy metabolism in HIV infection: a case studypt_BR
dc.typearticlept_BR

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