Charge transport in fibrous/not fibrous -helical and variant peptides

Bezerril, Leonardo Mafra; Fulco, Umberto Laino; Oliveira, Jonas Ivan Nobre; Corso, Gilberto; Albuquerque, Eudenilson Lins de; Freire, V. N.; Caetano, W. S.

Charge transport in fibrous/not fibrous -helical and variant peptides

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dc.contributor.author	Bezerril, Leonardo Mafra
dc.contributor.author	Fulco, Umberto Laino
dc.contributor.author	Oliveira, Jonas Ivan Nobre
dc.contributor.author	Corso, Gilberto
dc.contributor.author	Albuquerque, Eudenilson Lins de
dc.contributor.author	Freire, V. N.
dc.contributor.author	Caetano, W. S.
dc.date.accessioned	2020-12-11T16:23:41Z
dc.date.available	2020-12-11T16:23:41Z
dc.date.issued	2011-01-31
dc.description.resumo	Although differing only by the Ala→Gln substitution at the fifth or seventh position of the 3-peptide amino acid sequence Leu-Glu-Thr-Leu-Ala-Lys-Ala3, the 5Q3 variant forms fibrous assemblies more attenuated than those of the 3-peptide, while the 7Q3 variant does not form fibrils. A tight-binding transport modeling was performed to obtain their current-voltage patterns, with hopping energies of the dipeptides calculated within the density functional theory framework. Beyond the semiconductor character, we obtain that the current pattern can be used to distinguish them, suggesting that it can be useful for the development of devices as diagnostics tools for amyloidosislike diseases	pt_BR
dc.identifier.citation	BEZERRIL, L. M.; FULCO, U. L.; OLIVEIRA, J. I. N.; CORSO, G.; ALBUQUERQUE, E. L.; FREIRE, V. N.; CAETANO, E. W. S.. Charge transport in fibrous/not fibrous α3-helical and (5Q,7Q)α3 variant peptides. Applied Physics Letters, [S.L.], v. 98, n. 5, p. 053702-053702, 31 jan. 2011. Disponível em: https://aip.scitation.org/doi/10.1063/1.3551713. Acesso em: 16 out. 2020. http://dx.doi.org/10.1063/1.3551713.	pt_BR
dc.identifier.doi	10.1063/1.3551713
dc.identifier.issn	0003-6951
dc.identifier.issn	1077-3118
dc.identifier.uri	https://repositorio.ufrn.br/handle/123456789/30964
dc.language	en	pt_BR
dc.publisher	American Institute of Physics	pt_BR
dc.subject	Charge transport	pt_BR
dc.subject	Fibrous/not fibrous	pt_BR
dc.subject	Helical	pt_BR
dc.subject	Variant peptides	pt_BR
dc.title	Charge transport in fibrous/not fibrous -helical and variant peptides	pt_BR
dc.type	article	pt_BR