Red meat consumption, risk of incidence of cardiovascular disease and cardiovascular mortality, and the dose–response effect

dc.contributor.authorLima, Severina Carla Vieira Cunha
dc.contributor.authorMedeiros, Gidyenne Christine Bandeira Silva de
dc.contributor.authorAzevedo, Kesley Pablo Morais de
dc.contributor.authorMesquita, Gabriella Xavier Barbalho
dc.contributor.authorSilva, David Franciole de Oliveira
dc.contributor.authorPimenta, Isac Davidson Santiago Fernandes
dc.contributor.authorGonçalves, Ana Katherine da Silveira
dc.contributor.authorLyra, Clélia de Oliveira
dc.contributor.authorPiuvezam, Grasiela
dc.contributor.authorIDhttps://orcid.org/0000-0001-8268-1986pt_BR
dc.date.accessioned2025-02-20T20:02:17Z
dc.date.available2025-02-20T20:02:17Z
dc.date.issued2019
dc.description.resumoBackground: Red and (particularly) processed meats are high in cholesterol and saturated and solid fatty acids. Their consumption is considered one of the risk factors for metabolic disorders. Numerous studies demonstrated a possible association between red meat consumption and cardiovascular disease (CVD). In this protocol, we propose a systematic review of the literature to examine the associations of red meat consumption with CVD incidence and mortality, and explore the potential dose–response relationship. Methods: We will search MEDLINE/PubMed, Scopus, SciELO, LILACS, ScienceDirect, Web of Science, Cochrane (CENTRAL), WHOLIS, PAHO, and Embase. We will include prospective epidemiological studies (longitudinal cohort). Risk of bias will be assessed using the Newcastle-Ottawa scale (NOS). Four independent researchers will conduct all evaluations. Disagreements will be referred to a fifth reviewer. We will summarize our findings using a narrative approach and tables to describe the characteristics of the included studies. The heterogeneity between trial results will be evaluated using a standard chi-squared test with P < .05. We will conduct the study in accordance with the guideline of the Preferred Reporting Items for Systematic Review and Meta-analyses Protocols (PRISMA-P). Results: This review will evaluate the association between red meat consumption and incidence of CVD and mortality (primary outcome measures). The secondary outcome measure will include the dose–response effect. Conclusion: The findings of this systematic review will summarize the latest evidence of the association between red meat consumption and incidence of CVD and mortality and the dose–response effect through a systematic review and meta-analysis. Registration: PROSPERO CRD42019100914. Abbreviations: CVD = cardiovascular disease, NOS = Newcastle-Ottawa scale, PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyzes, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols.pt_BR
dc.identifier.citationMEDEIROS, Gidyenne Christine Bandeira Silva de; AZEVEDO, Kesley Pablo Morais de; MESQUITA, Gabriella Xavier Barbalho; LIMA, Severina Carla Vieira Cunha; SILVA, David Franciole de Oliveira; PIMENTA, Isac Davidson Santiago Fernandes; OLIVEIRA, Ana Katherine da Silveira; LYRA, Clélia de Oliveira; PIUVEZAM, Grasiela. Red meat consumption, risk of incidence of cardiovascular disease and cardiovascular mortality, and the dose?response effect Protocol for a systematic review and meta-analysis of longitudinal cohort studies. Medicines, v. 98, p. e17271, 2019. DOI: https://doi.org/10.1097/md.0000000000017271. Diponível em: https://journals.lww.com/md-journal/fulltext/2019/09200/red_meat_consumption,_risk_of_incidence_of.76.aspx. Acesso em 02 dez. 2024.pt_BR
dc.identifier.doihttps://doi.org/10.1097/md.0000000000017271
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/62779
dc.languageenpt_BR
dc.publisherMedicinespt_BR
dc.subjectCardiovascular diseasept_BR
dc.subjectCardiovascular mortalitypt_BR
dc.subjectProcessed meatpt_BR
dc.subjectProtocolpt_BR
dc.subjectRed meatpt_BR
dc.subjectUnprocessed red meatpt_BR
dc.titleRed meat consumption, risk of incidence of cardiovascular disease and cardiovascular mortality, and the dose–response effectpt_BR
dc.typearticlept_BR

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