Endovascular thrombectomy and medical therapy versus medical therapy alone in acute stroke: a randomized care trial”
| dc.contributor.author | Khoury, Naim N. | |
| dc.contributor.author | Darsaut, Tim E. | |
| dc.contributor.author | Ghostine, Jimmy | |
| dc.contributor.author | Deschaintre, Yan | |
| dc.contributor.author | Daneault, Nicole | |
| dc.contributor.author | Durocher, André | |
| dc.contributor.author | Lanthier, Sylvain | |
| dc.contributor.author | Poppe, Alexandre Y. | |
| dc.contributor.author | Odier, Céline | |
| dc.contributor.author | Lebrun, Louise-Hélène | |
| dc.contributor.author | Guilbert, François | |
| dc.contributor.author | Gentric, Jean-Christophe | |
| dc.contributor.author | Batista, André Lima | |
| dc.contributor.author | Weill, Alain | |
| dc.contributor.author | Roy, Daniel | |
| dc.contributor.author | Bracard, Serge | |
| dc.contributor.author | Raymond, Jean | |
| dc.date.accessioned | 2023-05-17T16:18:24Z | |
| dc.date.available | 2023-05-17T16:18:24Z | |
| dc.date.issued | 2017-09 | |
| dc.description.resumo | Background. – Until recently, the benefits of endovascular treatment in stroke were not proven. Care trials have been designed to simultaneously offer yet-to-be validated interventions and verify treatment outcomes. Our aim was to implement a care trial for patients with acute ischemic stroke. Methods. – The study was offered to all patients considered for endovascular management of acute ischemic stroke in one Canadian hospital. Inclusion criteria were broad: onset of symptoms ≤ 5 h or at any time in the presence of clinical-imaging mismatch and suspected or demonstrated proximal large vessel occlusion. Exclusion criteria were few: established infarction or hemorrhagic transforma tion of the target symptomatic territory and poor 3-month prognosis. The primary outcome was mRS ≤ 2 at 3 months. Patients were randomly allocated to standard care or standard care plus endovascular treatment. ClinicalTrials.gov: Identifier NCT02157532. Results. – Seventy-seven patients were recruited in 19 months (March 2013–October 2014) at a single center. Randomized allocation was interrupted when other trials showed the benefits of endovascular therapy. At 3 months, 20 of 40 patients (50.0%; 95% CI: 35%–65%) in the intervention group had reached the primary outcome, compared to 14 of 37 patients (37.8%; 95% CI: 24%–54%) in the control group (P = 0.36). Eleven patients in the intervention group died within 3 months compared to 9 patients in the standard care group. Conclusion. – A care trial was implemented to offer verifiable care to acute stroke patients. This approach offers a promising means to manage clinical dilemmas and guide uncertain practices. | pt_BR |
| dc.identifier.citation | KHOURY, Naim N.; DARSAUT, Tim E.; GHOSTINE, Jimmy; DESCHAINTRE, Yan; DANEAULT, Nicole; DUROCHER, André; LANTHIER, Sylvain; POPPE, Alexandre Y.; ODIER, Céline; LEBRUN, Louise-Hélène. Erratum to “Endovascular thrombectomy and medical therapy versus medical therapy alone in acute stroke: a randomized care trial⠽ Journal of Neuroradiol. 44 (2017) 198⠳202. Journal Of Neuroradiology, [S.L.], v. 44, n. 5, p. 351, set. 2017. Elsevier BV. DOI; http://dx.doi.org/10.1016/j.neurad.2017.05.005 | pt_BR |
| dc.identifier.doi | 10.1016/j.neurad.2017.01.126 | |
| dc.identifier.uri | https://repositorio.ufrn.br/handle/123456789/52461 | |
| dc.language | pt_BR | pt_BR |
| dc.subject | acute stroke | pt_BR |
| dc.subject | endovascular treatment | pt_BR |
| dc.subject | thrombectomy | pt_BR |
| dc.subject | randomized clinical trial | pt_BR |
| dc.title | Endovascular thrombectomy and medical therapy versus medical therapy alone in acute stroke: a randomized care trial” | pt_BR |
| dc.type | article | pt_BR |
Arquivos
Licença do Pacote
1 - 1 de 1
Nenhuma Miniatura disponível
- Nome:
- license.txt
- Tamanho:
- 1.45 KB
- Formato:
- Item-specific license agreed upon to submission
Nenhuma Miniatura disponível