Effects of zinc supplementation in patients with type 1 diabetes

dc.contributor.authorEvangelista, Karine Cavalcanti Maurício Sena
dc.contributor.authorArrais, Ricardo Fernando
dc.contributor.authorAlmeida, Maria das Graças
dc.contributor.authorAraújo, Dina Maria de
dc.contributor.authorSantos, Mirza Medeiros dos
dc.contributor.authorLima, Vanessa Teixeira de
dc.contributor.authorPedrosa, Lucia de Fátima Campos
dc.date.accessioned2024-08-26T23:17:04Z
dc.date.available2024-08-26T23:17:04Z
dc.date.issued2005
dc.description.resumoThe purpose of this study was to identify the effect of oral zinc supplementation in patients with type 1 diabetes (T1DM) on metabolic control and zinc blood concentrations. The sample consisted of 20 patients with T1DM and a control group (n=17). Metabolic control was evaluated by glycemia at fast, 24 h glycosuria, and HbA1c. Zinc concentrations were measured in plasma and erythrocytes. After the first collection of biological material, oral zinc supplementation was initiated and continued for 4 mo in T1MD patients (T1). Daily dosages were established based on Dietary Recommended Intakes (DRIs), considering zinc intake based on data from other studies previously performed with this population. All analyses were repeated after supplementation (T2). Metabolic control was unsatisfactory, with an HbA1c increase at T2. There was no difference in zinc concentrations in plasma and erythrocytes between patients with T1DM and control. Zinc concentrations in plasma were within the normal range in T1MD before and after supplementation and the control. Zinc concentrations in erythrocyte presented lower than normal values for all groups. A zinc increase in erythrocyte after supplementation was observed in T1DM patients, although without statistical significance. More studies are needed to confirm oral zinc supplementation as nutritional management in diabetespt_BR
dc.identifier.citationEVAGELISTA, Karine Cavalcanti Mauricio de Sena; ARRAIS, Ricardo Fernando; ALMEIDA, Maria das Graças; ARAUJO, Dina Maria de; SANTOS, Mirza Medeiros dos; LIMA, Vanessa Teixeira de; PEDROSA, Lucia de Fátima Campos. Effects of zinc supplementation in patients with type 1 diabetes. Biological Trace Element Research, [S.l.], v. 105, n. 1-3, p. 1-10, 2005. DOI: 10.1385/bter:105:1-3:001. Disponível em: https://pubmed.ncbi.nlm.nih.gov/16034148/. Acesso em: 26 jul. 2024.pt_BR
dc.identifier.doihttps://doi.org/10.1385/bter:105:1-3:001
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/59903
dc.languageenpt_BR
dc.publisherBiological Trace Element Researchpt_BR
dc.subjectZinc supplementationpt_BR
dc.subjectType 1 diabetespt_BR
dc.subjectMetabolic controlpt_BR
dc.subjectBlood zinc concentrationspt_BR
dc.subjectGlycemic managementpt_BR
dc.titleEffects of zinc supplementation in patients with type 1 diabetespt_BR
dc.typearticlept_BR

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