Os efeitos de terapias baseadas em mindfulness e doses de ayahuasca em traços de depressão e ansiedade

Abstract

Depression and anxiety are considered the evil of the century. The number of patients suffering from these disorders has increased considerably and tends to grow even more in the face of the stressful scenario of the contemporary world to which people have been increasingly exposed. About one-third of individuals diagnosed with anxiety or depression are resistant to antidepressant and anxiolytic drugs available on the market and do not present remission of symptoms even with medical follow-up. On this perspective, the number of researches that seek alternative methods to those traditionally used in the clinical routine for the treatment of anxiety and depression has increased. This review sought to gather clinical studies that describe the therapeutic pharmacological effects of ayahuasca, a drink with psychedelic properties originally consumed by Amazonian natives and religious communities; in parallel, analyzed clinical trials demonstrating the therapeutic effects of clinical interventions based on mindfulness-type meditation. From there, we compared the effects of the two proposals of alternative therapies on several biological markers, as well as proposals for a possible integration to reduce symptoms related to anxiety and depression.