Diagnosis and management of Guillain–Barré syndrome in ten steps

dc.contributor.authorDourado Junior, Mário Emílio Teixeira
dc.contributor.authorLeonhard, Sonja E.
dc.contributor.authorMandarakas, Melissa R.; et al.
dc.contributor.authorIDhttps://orcid.org/0000-0002-9462-2294pt_BR
dc.date.accessioned2023-07-27T18:26:27Z
dc.date.available2023-07-27T18:26:27Z
dc.date.issued2019
dc.description.resumoGuillain–Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and 2015 in Latin America. Diagnosis and management of GBS can be complicated as its clinical presentation and disease course are heterogeneous, and no international clinical guidelines are currently available. To support clinicians, especially in the context of an outbreak, we have developed a globally applicable guideline for the diagnosis and management of GBS. The guideline is based on current literature and expert consensus, and has a ten-step structure to facilitate its use in clinical practice. We first provide an introduction to the diagnostic criteria, clinical variants and differential diagnoses of GBS. The ten steps then cover early recognition and diagnosis of GBS, admission to the intensive care unit, treatment indication and selection, monitoring and treatment of disease progression, prediction of clinical course and outcome, and management of complications and sequelae.pt_BR
dc.identifier.citationDOURADO, Mario Emílio Teixeira, et al. Diagnosis and management of Guillain-Barré syndrome in ten steps. Nature Reviews Neurology, v. 15, p. 671-683, 2019. Disponível em: https://www.nature.com/articles/s41582-019-0250-9 Acesso em: 18 jul. 2023.pt_BR
dc.identifier.doihttps://doi.org/10.1038/ s41582-019-0250-9
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/54228
dc.languageenpt_BR
dc.publisherSpringerpt_BR
dc.subjectguillain–barré syndromept_BR
dc.subjectneuropatiapt_BR
dc.subjectimunoglobulina intravenosapt_BR
dc.titleDiagnosis and management of Guillain–Barré syndrome in ten stepspt_BR
dc.typearticlept_BR

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