Influência do exercício físico de alta intensidade em marcadores bioquímicos do perfis hepático, lipídico e renal

Abstract

High-intensity physical exercise promotes significant physiological adaptations but can also trigger biochemical changes that require detailed monitoring. This experimental study aimed to investigate the responses of biochemical markers such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), creatinine, urea, total cholesterol, HDL, non-HDL cholesterol, and triglycerides in physically active individuals subjected to high-intensity exercise. The study included 22 physically active male individuals aged 12 to 25, and the levels of these markers were analyzed at four distinct time points: before exercise, immediately after, two hours after, and 24 hours post-activity. The results showed significant changes in creatinine levels and triglyceride concentrations, which were not observed for the other markers. This pilot study contributed to understanding the acute effects of intense exercise on the hepatic, renal, and lipid systems, providing relevant data for the fields of exercise physiology and clinical biochemistry. However, studies with larger samples are necessary to confirm these findings and deepen the understanding of biochemical responses to high-intensity exercise.