Avaliação do drive inspiratório em pacientes pos-COVID

Abstract

Introduction: COVID-19 is an emerging infectious disease caused by SARS-CoV-2. The main signs and symptoms include fever, cough, dyspnea, and muscle fatigue, and may present mild, moderate, or severe complications. COVID-19 can cause lung and airway damage resulting in respiratory distress syndrome and, if severe, respiratory failure. This lung damage can also cause increased effort and respiratory drive. Thus, it is important to evaluate the changes after covid-19 contamination. Objectives: to evaluate the variables of respiratory impulse and respiratory muscle strength in patients after COVID-19 infection compared with healthy subjects and through the values found to verify these possible alterations. Methodology: Cross-sectional study, in which the subjects after COVID-19 infection and control group were evaluated in the tests of spirometry, airway occlusion pressure (P0.1), maximal inspiratory and expiratory pressures, and Nasal Inspiratory Pressure (SNIP). Results: Thirty-nine individuals were included after Covid-19, of whom 9 subjects were from the ICU group, 11 subjects were from the ward group and 19 were from the non-hospitalized group, and 8 individuals were from the control group. When each group was compared to covid-19 post-group with the control group by the T or Mann-Whitney test, a statistically significant difference was observed only in FVC1/FVC (p < 0.05). However, the values of P0.1 and respiratory muscle tension were elevated in the three groups after COVID-19. Conclusion: Individuals after COVID-19 infection did not present alterations in respiratory drive and respiratory muscle tension when compared to healthy individuals.