Extraction of bioactive alkaloids from Melocactus zehntneri using supercritical fluid

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dc.contributor.authorBrandão, Gustavo Henrique Azevedo
dc.contributor.authorRigo, Graziela Vargas
dc.contributor.authorRoque, A. A.
dc.contributor.authorSouza, A. C. D.
dc.contributor.authorScopel, Marina
dc.contributor.authorNascimento, Cláudio Augusto Oller do
dc.contributor.authorTasca, Tiana
dc.contributor.authorCourtial, Camila Gambini Pereira
dc.contributor.authorGiordani, Raquel Brandt
dc.date.accessioned2021-05-12T18:14:08Z
dc.date.available2021-05-12T18:14:08Z
dc.date.issued2017-11
dc.description.resumoThe purpose of this study was to extract alkaloids from Melocactus zehntneri aerial parts using supercrit-ical fluid extraction (SFE) and to evaluate their cytotoxic action. SFE process was compared to differentclassical low pressure solvent extraction processes in terms of global yield, extract profile and biologicalactivity. Two specimens of M. zehntneri were evaluated: young and adult aerial parts. The extracts wereanalyzed by HPLC-UV/DAD as well as they were evaluated against HMVII and Trichomonas vaginalis. Theresults indicated a qualitative difference in chromatographic profile of the extracts. Finally, the resultspoint out the potential of the extract obtained from aerial parts of young specimens (Y-RM) through SFEat 300 bar/55◦C against T. vaginalis and HMVII, presenting relevant information for development of newstudies about cytotoxicpt_BR
dc.identifier.citationBRANDÃO, G.H.A.; RIGO, G.; ROQUE, A.A.; SOUZA, A.C.D.; SCOPEL, M.; NASCIMENTO, C.A.O.; TASCA, T.; PEREIRA, C.G.; GIORDANI, R.B. . Extraction of bioactive alkaloids from Melocactus zehntneri using supercritical fluid. JOURNAL OF SUPERCRITICAL FLUIDS, v. 129, p. 28-35, 2017. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S0896844616305630?via%3Dihub. Acesso em: 05 abr. 2021. https://doi.org/10.1016/j.supflu.2016.12.012pt_BR
dc.identifier.doi10.1016/j.supflu.2016.12.012
dc.identifier.issn0896-8446
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/32508
dc.languageenpt_BR
dc.publisherElsevierpt_BR
dc.rightsAttribution 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/br/*
dc.subjectMelocactus zehntneript_BR
dc.subjectAlkaloidspt_BR
dc.subjectSupercritical fluidspt_BR
dc.subjectTrichomonas vaginalispt_BR
dc.subjectHMVIIapt_BR
dc.titleExtraction of bioactive alkaloids from Melocactus zehntneri using supercritical fluidpt_BR
dc.typearticlept_BR

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