Retinol status and associated factors in mother–newborn pairs

dc.contributor.authorRibeiro, Karla Danielly da Silva
dc.contributor.authorBezerra, Danielle Soares
dc.contributor.authorLima, Mayara Santa Rosa
dc.contributor.authorMedeiros, Jeane Franco Pires
dc.contributor.authorSilva, Ana Gabriela Corrêa da
dc.contributor.authorDimenstein, Roberto
dc.contributor.authorOsório, Mônica Maria
dc.contributor.authorIDhttps://orcid.org/0000-0002-2251-5967
dc.contributor.authorIDhttps://orcid.org/0000-0003-2204-8622
dc.date.accessioned2025-06-25T23:50:58Z
dc.date.available2025-06-25T23:50:58Z
dc.date.issued2019-10-11
dc.description.resumoBackground: Vitamin A deficiency is still considered to be a nutritionalproblem during pregnancy, lactation and early childhood. The present studyaimed to assess the vitamin A status of women and their newborns in the Brazilian Northeast and to determine the association between retinol in thematernal serum, umbilical cord blood and colostrum. Methods: Vitamin A status in 65 pairs of women and newborns was assessed from samples of the mother’s serum, umbilical cord serum and colostrum using high-performance liquid chromatography. The inadequacy of the vitamin A status of mothers and infants was identified if the retinolvalues were <0.7 µmol L-1 in maternal serum or umbilical cord blood or<1.05 µmol L-1 in colostrum. Results: The prevalence of inadequate maternal vitamin A status was 21.5%(95% CI: 11.5%–31.5%) and 13.8% [95% confidence interval (CI) = 5.4%–22.2%] based on maternal serum and colostrum, respectively. Among new-borns, 41.5% (95% CI = 29.3%–53.5%) presented a low status of vitamin A based on cord serum. Multiple linear regression analysis identified that maternal serum retinol is a predictor of umbilical cord retinol (P = 0.005).Retinol in maternal serum was lower in mothers who were less educated (P = 0.04) and colostrum retinol was higher in older (P = 0.04) and multi-parous (P = 0.002) mothers. Conclusions: Vitamin A deficiency is a common problem among mothers attended in public hospitals in Northeast Brazil and maternal retinol concentrations are associated with retinol status in newborns. Maternal age, parity and educational level were related to the maternal vitamin A status
dc.identifier.citationBEZERRA, Danielle Soares, RIBEIRO, Karla Danielly da Silva; LIMA, Mayara Santa Rosa; MEDEIROS, Jeane Franco Pires; SILVA, Ana Gabriela Corrêa da; DIMENSTEIN, Roberto; OSÓRIO, Mônica Maria. Retinol status and associated factors in mother-newborn pairs. Journal of Human Nutrition and Dietetics, p. 1-10, 2019. DOI: http://dx.doi.org/10.1111/jhn.12707. Disponível em: https://onlinelibrary.wiley.com/doi/10.1111/jhn.12707. Acesso em: 07 out. 2024.
dc.identifier.otherhttp://dx.doi.org/10.1111/jhn.12707
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/64036
dc.language.isoen_US
dc.publisherJournal of Human Nutrition and Dietetics
dc.subjectVitamin A
dc.subjectSerum
dc.subjectUmbilical cord
dc.subjectColostrum
dc.subjectHigh-performance liquid chromatography
dc.titleRetinol status and associated factors in mother–newborn pairs
dc.typearticle

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