Factors associated with mortality of elderly people due to COVID-19: protocol for systematic review and meta-analysis

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dc.contributor.authorMedeiros, Gidyenne Christine Bandeira Silva de
dc.contributor.authorSilva Júnior, Danyllo do Nascimento
dc.contributor.authorMata, Ádala Nayana de Sousa
dc.contributor.authorMarques, Marilane Vilela
dc.contributor.authorSantos, Thais Teixeira dos
dc.contributor.authorMonteiro, Maria Eduarda de Sousa
dc.contributor.authorCosta, Gabriela Góis
dc.contributor.authorD'orsi, Eleonora
dc.contributor.authorParra, Eva Vegue
dc.contributor.authorPiuvezam, Grasiela
dc.date.accessioned2024-07-30T22:26:28Z
dc.date.available2024-07-30T22:26:28Z
dc.date.issued2024-04
dc.description.resumoIntroduction The COVID-19 pandemic has become a significant health crisis, marked by high mortality rates on a global scale, with mortality from the disease being notably concentrated among the elderly due to various factors. Objective This study aims to investigate the biological and non-biological factors associated with COVID-19 mortality rates among the elderly worldwide. Methods The following databases will be consulted: PubMed, Scopus, EMBASE, Web of Science and ScienceDirect. Longitudinal observational studies (cohort and case-control—risk factors) will be included. The risk of bias, defined as low, moderate, high, will be assessed using the National Heart, Lung and Blood Institute (NHLBI) Quality Assessment Tool for observational cohort and cross-sectional studies. Two independent authors will conduct the searches, and any possible disagreements will be resolved by a third author. Heterogeneity between study results will be assessed using a standard X2 test with a significance level of 0.05, and an I 2 value will be calculated to further assess heterogeneity. The random effects model for meta-analyses will be adopted to distribute the weight between the studies and standardize their contributions. The meta-analyses will be conducted using RevMan software. Discussion Despite the numerous publications on COVID-19 mortality among the elderly, there is still a gap in knowledge, as there is no systematic review and meta-analysis that summarizes the main biological and non-biological associated factors globally. Conclusion The results of this study will consolidate the latest evidence and address gaps in the overall understanding of biological or non-biological associated factors. This knowledge will facilitate the development of appropriate health strategies for this demographic group and pave the way for further researchpt_BR
dc.identifier.citationSILVA JUNIOR, Danyllo do Nascimento; MATA, Ádala Nayana de Sousa; MEDEIROS, Gidyenne Christine Bandeira Silva de; MARQUES, Marilane Vilela; SANTOS, Thais Teixeira dos; MONTEIRO, Maria Eduarda de Sousa; COSTA, Gabriela Góis; D'ORSI, Eleonora; PARRA, Eva Vegue; PIUVEZAM, Grasiela. Factors associated with mortality of elderly people due to COVID-19: protocol for systematic review and meta-analysis. Plos One, [S.l.], v. 19, n. 4, p. 1-9, 18 abr. 2024. DOI: 10.1371/journal.pone.0289576. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0289576. Acesso em: 10 jul. 2024.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1371/journal.pone.0289576
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/58909
dc.languageenpt_BR
dc.publisherPlos Onept_BR
dc.rightsAttribution 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/br/*
dc.subjectCOVID-19pt_BR
dc.subjectElderlypt_BR
dc.subjectMortalitypt_BR
dc.subjectRisk factorspt_BR
dc.subjectSystematic reviewpt_BR
dc.titleFactors associated with mortality of elderly people due to COVID-19: protocol for systematic review and meta-analysispt_BR
dc.typearticlept_BR

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