On the Role of Retrosplenial Cortex in Long-Lasting Memory Storage

dc.contributor.authorKatche, Cynthia
dc.contributor.authorDorman, Guido
dc.contributor.authorGonzalez, Carolina
dc.contributor.authorKramar, Cecilia P.
dc.contributor.authorSlipczuk, Leandro
dc.contributor.authorRossato, Janine I.
dc.contributor.authorCammarota, Martín Pablo
dc.contributor.authorMedina, Jorge H.
dc.date.accessioned2017-05-31T17:01:28Z
dc.date.available2017-05-31T17:01:28Z
dc.date.issued2013
dc.description.resumoThe retrosplenial cortex (RSC) is involved in a range of cognitive functions. However, its precise involvement in memory processing is unknown. Pharmacological and behavioral experiments demonstrate that protein synthesis and c-Fos expression in the anterior part of RSC (aRSC) are necessary late after training to maintain for many days a fear-motivated memory. Long-lasting memory storage is regulated by D1/ D5 dopamine receptors in aRSC and depends on the functional interplay between dorsal hippocampus and aRSC. These results suggest that the RSC recapitulates some of the molecular events that occur in the hippocampus to maintain memory trace over time.pt_BR
dc.identifier.issn1050-9631
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/23288
dc.languageengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectprotein synthesispt_BR
dc.subjectc-Fospt_BR
dc.subjecthippocampuspt_BR
dc.subjectmemory persistencept_BR
dc.subjectdopaminept_BR
dc.titleOn the Role of Retrosplenial Cortex in Long-Lasting Memory Storagept_BR
dc.typearticlept_BR

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