Synthesis and characterization of xylan-coated magnetite microparticles

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dc.contributor.authorAraújo, Jose Humberto de
dc.contributor.authorSilva, Amanda Karina Andriola
dc.contributor.authorSilva, Érica L. da
dc.contributor.authorOliveira, Elquio Eleamen
dc.contributor.authorSoares, Luiz Alberto Lira
dc.contributor.authorNagashima Junior, Toshiyuiky
dc.contributor.authorMedeiros, Aldo C.
dc.contributor.authorAraújo, Ivonete Batista de
dc.contributor.authorCarriço, Artur Silva
dc.contributor.authorEgito, Eryvaldo Sócrates Tabosa do
dc.date.accessioned2020-06-18T15:07:47Z
dc.date.available2020-06-18T15:07:47Z
dc.date.issued2006-10-13
dc.description.resumoThis work evaluates an experimental set-up to coat superparamagnetic particles in order to protect them from gastric dissolution. First, magnetic particles were produced by coprecipitation of iron salts in alkaline medium. Afterwards, an emulsification/cross-linking reaction was carried out in order to produce magnetic polymeric particles. The sample characterization was performed by X-ray powder diffraction, laser scattering particle size analysis, optical microscopy, thermogravimetric analysis and vibrating sample magnetometry. In vitro dissolution tests at gastric pH were evaluated for both magnetic particles and magnetic polymeric particles. The characterization data have demonstrated the feasibility of the presented method to coat, and protect magnetite particles from gastric dissolution. Such systems may be very promising for oral administrationpt_BR
dc.identifier.citationSILVA, A; DASILVA, E; OLIVEIRA, E; NAGASHIMAJR, T; SOARES, L; MEDEIROS, A ; ARAUJO, J; ARAUJO, I; CARRICO, A; EGITO, E. Synthesis and characterization of xylan-coated magnetite microparticles. International Journal of Pharmaceutics, v. 334, p. 42-47, 2007. Disponivel em: https://www.sciencedirect.com/science/article/pii/S0378517306008854?via%3Dihub#! Acesso em: 01 jun 2020. https://doi.org/10.1016/j.ijpharm.2006.10.019pt_BR
dc.identifier.doi10.1016/j.ijpharm.2006.10.019
dc.identifier.issn0378-5173
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/29300
dc.languageenpt_BR
dc.publisherInternational Journal of Pharmaceuticspt_BR
dc.subjectMagnetic particlespt_BR
dc.subjectGastric dissolutionpt_BR
dc.subjectPolymeric coatingpt_BR
dc.subjectXylanpt_BR
dc.titleSynthesis and characterization of xylan-coated magnetite microparticlespt_BR
dc.typearticlept_BR

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