Collapsing glomerulopathy: a review by the collapsing brazilian consortium

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dc.contributor.authorAlmeida, Jose Bruno de
dc.contributor.authorCutrim, Érico Murilo Monteiro
dc.contributor.authorNeves, Precil Diego Miranda de Meneses
dc.contributor.authorCampos, Marcos Adriano Garcia
dc.contributor.authorWanderley, Davi Campos
dc.contributor.authorTeixeira Júnior, Antonio Augusto Lima
dc.contributor.authorMuniz, Monique Pereira Rêgo
dc.contributor.authorLadchumananandasivam, Francisco Rasiah
dc.contributor.authorGomes, Orlando Vieira
dc.contributor.authorVasco, Rafael Fernandes Vanderlei
dc.contributor.authorBrito, Dyego José de Araújo
dc.contributor.authorLages, Joyce Santos
dc.contributor.authorSalgado-Filho, Natalino
dc.contributor.authorGuedes, Felipe Leite
dc.contributor.authorMagalhães, Marcelo
dc.contributor.authorAraújo, Stanley de Almeida
dc.contributor.authorSilva, Gyl Eanes Barros
dc.date.accessioned2023-08-02T19:00:51Z
dc.date.available2023-08-02T19:00:51Z
dc.date.issued2022
dc.description.resumoCollapsing glomerulopathy (CG) is a clinicopathologic entity characterized by segmentar or global collapse of the glomerulus and hypertrophy and hyperplasia of podocytes. The Columbia classification of 2004 classified CG as a histological subtype of focal segmental glomerulosclerosis (FSGS). A growing number of studies have demonstrated a high prevalence of CG in many countries, especially among populations with a higher proportion of people with African descent. The present study is a narrative review of articles extracted from PubMed, Medline, and Scielo databases from September 1, 2020 to December 31, 2021. We have focused on populational studies (specially cross-sectional and cohort articles). CG is defined as a podocytopathy with a distinct pathogenesis characterized by strong podocyte proliferative activity. The most significant risk factors for CG include APOL1 gene mutations and infections with human immunodeficiency virus and severe acute respiratory syndrome coronavirus 2. CG typically presents with more severe symptoms and greater renal damage. The prognosis is notably worse than that of other FSGS subtypespt_BR
dc.identifier.citationALMEIDA, José Bruno, et. al. Collapsing Glomerulopathy: A Review by the Collapsing Brazilian Consortium. Frontiers In Medicine, v. 9, p. 846173, 2022.DOI: https://doi.org/10.3389/fmed.2022.846173 Disponível em: https://observatorio.fm.usp.br/handle/OPI/48634 Acesso em: 27 jul. 2023pt_BR
dc.identifier.doihttps://doi.org/10.3389/fmed.2022.846173
dc.identifier.urihttps://repositorio.ufrn.br/handle/123456789/54341
dc.languageenpt_BR
dc.publisherFrontiers in medicinept_BR
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcollapsing glomerulopathypt_BR
dc.subjectsegmental and focal glomerulosclerosispt_BR
dc.subjectnephrotic syndrome (NS)pt_BR
dc.subjectrenal biopsypt_BR
dc.subjectpodocytespt_BR
dc.subjectglomerulopathypt_BR
dc.titleCollapsing glomerulopathy: a review by the collapsing brazilian consortiumpt_BR
dc.typearticlept_BR

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