Medial prefrontal cortex is a crucial node of a rapid learning system that retrieves recent and remote memories

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dc.contributor.authorGonzalez, Carolina
dc.contributor.authorKramar, Cecilia
dc.contributor.authorGaragoli, Fernando
dc.contributor.authorRossato, Janine I.
dc.contributor.authorWeisstaub, Noelia
dc.contributor.authorCammarota, Martín Pablo
dc.contributor.authorMedina, Jorge H.
dc.date.accessioned2017-06-01T12:39:45Z
dc.date.available2017-06-01T12:39:45Z
dc.date.issued2013
dc.description.resumoThe neocortex is thought to be a distributed learning system that gradually integrates semantic information into the initial mnemonic representation rapidly formed by the hippocampus after acquisition. Nevertheless, an emerging view suggests that some cortical regions, in particular the medial prefrontal cortex (mPFC), may also have a role during the initial steps of memory consolidation as well as in the recall of recent memories. Here, we show that mPFC plays a critical role during the first few hours of inhibitory avoidance memory consolidation and is necessary for the normal retrieval of both recent and remote memories, supporting the idea that involvement of neocortical areas in memory processing is not restricted to the late post-training consolidation phase.pt_BR
dc.identifier.doi10.1016/j.nlm.2013.04.006
dc.identifier.urihttps://repositorio.ufrn.br/jspui/handle/123456789/23331
dc.languageengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectMedial prefrontal cortexpt_BR
dc.subjectHippocampuspt_BR
dc.subjectMemory consolidationpt_BR
dc.subjectMemory retrievalpt_BR
dc.subjectInhibitory avoidancept_BR
dc.titleMedial prefrontal cortex is a crucial node of a rapid learning system that retrieves recent and remote memoriespt_BR
dc.typearticlept_BR

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