Navegando por Autor "Silva, Eduardo Paixão da"
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TCC Avaliação do status de zinco considerando diferentes combinações de componentes na síndrome metabólica(Universidade Federal do Rio Grande do Norte, 2017-11-28) Silva, Eduardo Paixão da; Sena-Evangelista, Karine Cavalcanti Maurício de; Freitas, Erika Paula Silva; Vale, Sancha Helena de LimaOs fatores cardiometabólicos característicos da síndrome metabólica (SM) apresentam influência no metabolismo do zinco, de forma isolada ou conjuntamente. Sendo assim, o status de zinco pode variar, dependendo da combinação de componentes, explicando em parte as divergências sobre o status de zinco nesses indivíduos. O presente estudo objetivou comparar as concentrações de zinco no plasma e zinco da dieta entre os grupos de indivíduos com SM, considerando o número de componentes utilizados para o seu diagnóstico. O estudo transversal incluiu 88 indivíduos adultos e idosos com SM, de ambos os sexos, diagnosticados segundo o National Cholesterol Education Program – Adult Treatment Panel III. Definiu-se os grupos, considerando a junção de três (n=36), quatro (n=40) e cinco componentes da SM (n=12). O zinco da dieta foi avaliado a partir de dois recordatórios de 24h e os dados foram analisados no software Virtual Nutri Plus 2.0®. Foram realizadas medidas da pressão arterial, perímetro da cintura e avaliadas a glicemia de jejum, colesterol da lipoproteína de alta densidade, triglicerídeos. A dosagem de zinco no plasma foi realizada por meio de espectrofotometria de absorção atômica, considerando 70-110 μg/dL como referência. Realizou-se análises descritivas e as comparações entre os três grupos se deu por meio do teste ANOVA, seguido do teste Tukey. A média de idade dos pacientes foi de 50 (11) anos, com predominância do sexo feminino (72%). Observou-se no grupo que apresenta 3 componentes, 10 diferentes combinações de fenótipos, com destaque para a combinação: hipertensão arterial ou pressão arterial elevada, diabetes mellitus tipo 2 ou glicemia de jejum elevada e perímetro da cintura aumentado (11,4%). No grupo com 4 componentes, houve predominância do mesmo fenótipo com acréscimo do HDL-c baixo (18,2%). Constatou-se percentuais de inadequação no consumo de zinco de 75%, 73,6% e 66,6% nos grupos com 3, 4 e 5 componentes, respectivamente. Não foram verificadas diferenças significativas nos valores de zinco no plasma entre os grupos com 3, 4 e 5 componentes, apresentando médias de 92,62(18,26) μg/dL; 86,24(17,88) μg/dL; 86,94(17,12) μg/dL, respectivamente (p>0,05). No entanto, observou-se concentrações de zinco no plasma <70μg/dL em 11,1% de indivíduos no grupo com 3 componentes, em comparação a 15,8% no grupo com 4 componentes e 16,7% nos indivíduos pertencentes ao grupo com 5 componentes. Conclui-se que indivíduos com SM apresentam baixa ingestão de zinco da dieta e concentrações de zinco no plasma dentro da normalidade, independentemente do número de componentes.Artigo Lack of association between inadequate micronutrient intake and prognosis in outpatients with heart failure(Nutrients, 2022) Lima, Severina Carla Vieira Cunha; Torres, Núbia Rafaella Soares Moreira; Freire, Fernanda Lambert de Andrade; Komatsu, Raquel Costa Silva Dantas; Silva, Eduardo Paixão da; Queiroz, Salomão Israel Monteiro Lourenço; Lira, Niethia Regina Dantas de; Diniz, Rosiane Viana Zuza; Pedrosa, Lucia Fatima Campos; Lopes, Márcia Marília Gomes Dantas; Evangelista, Karine Cavalcanti Maurício Sena; https://orcid.org/0000-0001-8268-1986Inadequate nutrient intake can lead to worse outcomes in patients with heart failure (HF). This prospective cohort study aimed to assess the prevalence of inadequate micronutrient intake and their association with prognosis in 121 adult and elderly outpatients with HF. Habitual micronutrient intake was evaluated using 24-h dietary recalls (minimum 2 and maximum 6). Participants were grouped into moderate (n = 67) and high (n = 54) micronutrient deficiency groups, according to the individual assessment of each micronutrient intake. Patients’ sociodemographic, clinical, and anthropometric data and clinical outcomes (hospitalization and mortality) within 24 months were collected. Overall and event-free survival rates were calculated using Kaplan–Meier estimates, and curves were compared using the log-rank test. The death risk rate (hazard ratio (HR)) was calculated using Cox’s univariate model. The rate of inadequate intake was 100% for vitamins B1 and D and above 80% for vitamins B2, B9, and E, calcium, magnesium, and copper. No differences in overall survival and event-free survival were observed between groups of HF outpatients with moderate and high micronutrient deficiencies (HR = 0.94 (CI = 0.36–2.48), p = 0.91, and HR = 1.63 (CI = 0.68–3.92), p = 0.26, respectively), as well as when the inadequacy of each micronutrient intake was evaluated alone (all p > 0.05). In conclusion, a high prevalence of inadequate micronutrient intake was observed in outpatients with HF. Inadequate micronutrient intake was not associated with hospitalization and mortality in this group of patients.Artigo Lack of association between inadequate micronutrient Intake and prognosis in outpatients with heart failure(Nutrients, 2022) Lopes, Márcia Marília Gomes Dantas; Torres, Núbia Rafaella Soares Moreira; Freire, Fernanda Lambert de Andrade; Komatsu, Raquel Costa Silva Dantas; Silva, Eduardo Paixão da; Queiroz, Salomão Israel Monteiro Lourenço; Lira, Niethia Regina Dantas de; Diniz, Rosiane Viana Zuza; Lima, Severina Carla Vieira Cunha; Pedrosa, Lucia Fatima Campos; Evangelista, Karine Cavalcanti Maurício Sena; https://orcid.org/0000-0002-0011-576XInadequate nutrient intake can lead to worse outcomes in patients with heart failure (HF). This prospective cohort study aimed to assess the prevalence of inadequate micronutrient intake and their association with prognosis in 121 adult and elderly outpatients with HF. Habitual micronutrient intake was evaluated using 24-h dietary recalls (minimum 2 and maximum 6). Participants were grouped into moderate (n = 67) and high (n = 54) micronutrient deficiency groups, according to the individual assessment of each micronutrient intake. Patients’ sociodemographic, clinical, and anthropometric data and clinical outcomes (hospitalization and mortality) within 24 months were collected. Overall and event-free survival rates were calculated using Kaplan–Meier estimates, and curves were compared using the log-rank test. The death risk rate (hazard ratio (HR)) was calculated using Cox’s univariate model. The rate of inadequate intake was 100% for vitamins B1 and D and above 80% for vitamins B2, B9, and E, calcium, magnesium, and copper. No differences in overall survival and event-free survival were observed between groups of HF outpatients with moderate and high micronutrient deficiencies (HR = 0.94 (CI = 0.36–2.48), p = 0.91, and HR = 1.63 (CI = 0.68–3.92), p = 0.26, respectively), as well as when the inadequacy of each micronutrient intake was evaluated alone (all p > 0.05). In conclusion, a high prevalence of inadequate micronutrient intake was observed in outpatients with HF. Inadequate micronutrient intake was not associated with hospitalization and mortality in this group of patients.