Navegando por Autor "Ohara, Daniel T."

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SPLOOCE: A new portal for the analysis of human splicing variants
(2012-11) Kroll, José Eduardo; Galante, Pedro A. F.; Ohara, Daniel T.; Navarro, Fábio C. P.; Ohno-Machado, Lucila; Souza, Sandro José de
Understanding alternative splicing is crucial to elucidate the mechanisms behind several biological phenomena, including diseases. The huge amount of expressed sequences available nowadays represents an opportunity and a challenge to catalog and display alternative splicing events (ASEs). Although several groups have faced this challenge with relative success, we still lack a computational tool that uses a simple and straightforward method to retrieve, name and present ASEs. Here we present SPLOOCE , a portal for the analysis of human splicing variants. SPLOOCE uses a method based on regular expressions for retrieval of ASEs. We propose a simple syntax that is able to capture the complexity of ASEs.

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