Navegando por Autor "Medeiros, Aldo Cunha"
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Artigo Biodistribution of samarium-153-EDTMP in rats treated with docetaxel(2009) Villarim Neto, Arthur; Açucena, Maria Kadja Meneses Torres; Pereira, Kércia Regina Santos Gomes; Rêgo, Amália Cínthia Meneses; Azevedo, Ítalo Medeiros; Bernardo Filho, Mário; Medeiros, Aldo CunhaArtigo Biodistribution of technetium-99m pertechnetate after Roux-en-Y gastric bypass (Capella technique) in rats(2010) Rêgo, Amália Cínthia Meneses do; Araújo Filho, Irami; Azevedo, Ítalo Medeiros; Jácome, Daniel Tôrres; Ramalho, Rachel de Alcântara Oliveira; Medeiros, Aldo CunhaArtigo Biodistribution of the radiophamarceutical sodium pertechnetate (Na99mTcO4) after massive small bowel resection in rats(2007) Chacon, Dâmaso de Araújo; Araújo Filho, Irami; Villarim Neto, Arthur; Rêgo, Amália Cínthia Meneses; Azevedo, Ítalo Medeiros; Bernardo Filho, Mário; Brandão Neto, José; Medeiros, Aldo CunhaArtigo Biodistribution of the Radiopharmaceutical Sodium Pertechnetate after Biliopancreatic Bypass with a Duodenal Switch(2007) Araújo Filho, Irami; Rêgo, Amália Cínthia Meneses; Brandão Neto, José; Villarim Neto, Arthur; Egito, Eryvaldo Sócrates Tabosa; Azevedo, Ítalo Medeiros; Medeiros, Aldo CunhaArtigo Biodistribution of the Radiopharmaceutical Technetium- 99m-Sodium Phytate in Rats After Splenectomy(2008) Pereira, Kércia Regina Santos Gomes; Açucena, Maria Kadja Meneses Torres; Villarim Neto, Arthur; Rêgo, Amália Cínthia Meneses; Bernardo Filho, Mário; Azevedo, Ítalo Medeiros; Araújo Filho, Irami; Medeiros, Aldo CunhaArtigo Efeito da sinvastatina na sepse abdominal de ratos diabéticos(2010) Araújo Filho, Irami; Jácome, Daniel Torres; Rêgo, Amália Cínthia Meneses do; Azevedo, Ítalo Medeiros; Egito, Eryvaldo Sócrates Tabosa; Medeiros, Aldo CunhaArtigo Efeitos da aplicação tópica do mel de melipona subnitida em feridas infectadas de ratos(2008) Alves, Diego Felipe Sampaio; Cabral Júnior, Francisco das Chagas; Cabral, Pedro Paulo de Arruda Câmara; Oliveira Junior, Ruy Medeiros de; Rego, Amália Cínthia Meneses do; Medeiros, Aldo CunhaArtigo Effect of hydration with Ringer's solution submitted to magnetic field in an experimental model of hepatic ischemia-reperfusion injury in rats(JOURNAL OF SURGICAL AND CLINICAL RESEARCH, 2018-11-09) Carriço, Artur da Silva; Azevedo, Ítalo Medeiros de; Freire, Juliana Mendonça; Souza, Jeovana Pinheiro Fernandes; Azevedo, Fabio Medeiros de; Medeiros, Aldo CunhaPurpose:To evaluate the effect of hydration with Ringer's solution submitted to magnetic field in experimental model of hepatic ischemia/reperfusion in rats. Methods:Wistar rats weighing 389.58±46.88g were randomly allocated into 2 groups: control group (n = 6) -Hepatic ischemia/reperfusion and hydration with Ringer's solution; and test group (n = 6) -Hepatic ischemia/reperfusion and hydration with Ringer submitted to magnetic field of 20 mT during 2 hours. After anesthesia with ketamine 70 mg/kg and xylazine 7mg/kg i.p., the animals were weighed and operated by aseptic technique. The ischemia of the median and left liver lobes was induced for 30 minutes using a vascular clip. Then, i.v. hydration with 3 ml of Ringer in the control group, and 3 ml of magnetizedRinger’s solution in the test group. After 24 hours, blood sample and fragment of the left liver lobe were collected for the determination of AST, ALT, ALP and albumin levels, and histopathological examination. Results:There was no significant differencein comparison of the rats weight loss, biochemical measurements and histopathological scores between the groups (p>0.05). Conclusion:The hydration with Ringer's solution submitted to magnetic field after hepatic ischemia/reperfusion in rats did not alterliver unction tests neither histopathological scores, comparing with the control group.Artigo Effect of Ringer's solution submitted to magnetic field in renal ischemia-reperfusion model in rats(JOURNAL OF SURGICAL AND CLINICAL RESEARCH, 2018-11-09) Carriço, Artur da Silva; Medeiros, Aldo Cunha; Souza, Jeovana Pinheiro Fernandes de; Freire, Juliana Mendonça; Azevedo, Italo Medeiros; Azevedo, Fabio Medeiros dePurpose: To evaluate the effect of hydration with simple Ringer's solution submitted to magnetic field in rats under renal ischemia and reperfusion (I/R) model, using biochemical and histopathological evaluation. Methods: Wistar rats were allocated into 2 equal groups of 6 animals each: Renal ischemia/reperfusion group + hydration with magnetic Ringer (mag Ringer). The left kidney underwent ischemia for 30 minutes. The right kidney was not manipulated. Thereafter, i.v. hydration was performed with 3 ml mag Ringer; Group renal I/R + hidration with simple Ringer. The simple Ringer solution was submitted to a magnetic field of 20mT intensity for 2 hours immediately prior to the surgical procedure. After 24 hours, under anesthesia blood was collected for dosing serum urea and creatinine. Histopathological analysis was performed on the left kidney (HE staining). Results: There was no significant difference between the creatinine (p=0.764) and urea (p = 0.926) values between the control and test groups (non-parametric Mann-Whitney test). Comparing the histopathological scores, there was a significant difference between the groups, with higher levels of lesions in the mag Ringer treated group (p=0.025) - Mann-Whitney test. Conclusion: The use of Ringer's solution submitted to magnetic field for intravenous hydration in a renal ischemia/reperfusion model did not alter the renal function and had a negative influence on the histopathological findings on the kidney, when compared to control.Artigo Effect of sildenafil in renal ischemia/reperfusion injury in rats(2010) Medeiros, Paulo José de; Neto, Arthur Villarim; Lima, Francisco Pignataro; Azevedo, Ítalo Medeiros; Leão, Layra Ribeiro de Sousa; Medeiros, Aldo CunhaArtigo Effect of Tripanosomicide Benznidazole (Rochagan®) on the Biodistribution of Sodium Pertechnetate (Na99mTcO4) in Wistar Rats(2008) Barbosa, Vanessa Santos de Arruda; Holanda, Cecília Maria de Carvalho Xavier; Silva, Roseane Pereira da; Oliveira, Daniel Pereira de; Silva Júnior, Maurício Ferreira da; Oliveira, Elias Herculano de; Spyrides, Maria Helena Constantino; Medeiros, Aldo CunhaArtigo Effects of Purified Saccharomyces cerevisiae (1→3)-β-Glucan on Venous Ulcer Healing(2012) Medeiros, Sarah Dantas Viana; Cordeiro, Sara Lima; Cavalcanti, Jéssica Escorel Chaves; Melchuna, Karina Mendes; Lima, Aleida Maria da Silva; Araújo Filho, Irami; Medeiros, Aldo Cunha; Rocha, Keyla Borges Ferreira; Oliveira, Elizabeth Maia; Faria, Eduardo Dantas Baptista; Sassaki, Guilherme Lanzi; Rocha, Hugo Alexandre Oliveira; Sales, Valéria Soraya FariasArtigo Effects of Purified Saccharomyces cerevisiae (1→3)-β-Glucan on Venous Ulcer Healing(2012-07-02) Medeiros, Sarah Dantas Viana; Cordeiro, Sara Lima; Cavalcanti, Jéssica Escorel Chaves; Melchuna, Karina Mendes; Lima, Aleida Maria da Silva; Araújo Filho, Irami; Medeiros, Aldo Cunha; Rocha, Keyla Borges Ferreira; Oliveira, Elizabeth Maia; Faria, Eduardo Dantas Baptista; Sassaki, Guilherme Lanzi; Rocha, Hugo Alexandre Oliveira; Sales, Valéria Soraya FariasArtigo Effects of simvastatin in abdominal sepsis in rats(2006) Souza Neto, José Luiz de; Araújo Filho, Irami; Rego, Amália Cínthia Meneses do; Dominici, Víctor Almeida; Azevedo, Ítalo Medeiros; Egito, Eryvaldo Sócrates Tabosa; Brandão Neto, José; Medeiros, Aldo CunhaArtigo Effects of the basic fibroblast growth factor and its anti-factor in the healing and collagen maturation of infected skin wound(Acta Cirúrgica Brasileira, 2007) Dantas Filho, Antonio Medeiros; Aguiar, Jose Lamartine de Andrade; Rocha, Luís Reginaldo de Menezes; Azevedo, Italo Menezes; Medeiros, Aldo CunhaArtigo Hiperhidrose compensatória após simpatectomia toracoscópica: características, prevalência e influência na satisfação do paciente(Jornal Brasileiro de Pneumologia, 2009) Araújo, Carlos Alberto Almeida de; Azevedo, Ítalo Medeiros; Ferreira, Maria Angela Fernandes; Ferreira, Hylas Paiva da Costa; Dantas, Jorge Lúcio Costa de Medeiros; Medeiros, Aldo CunhaObjetivo: Trabalho com o objetivo de analisar a freqüência e intensidade de estenose traqueal após ressecção e anastomose sob tensão; ação da metilprednisolona como agente profilático da estenose traqueal e a caracterização dos fenômenos da cicatrização com e sem o uso de corticóide. Métodos: Foram utilidados 20 cães mestiços pesando 13±5 Kg divididos aleatoriamente em dois grupos. No grupo A(n=10) não foi usado corticóide (controle). No grupo B foi usada a metilprednisolona IM na dose 10mg/Kg. Sob anestesia geral com intubação orotraqueal foram ressecados 3 anéis traqueais de todos animais, de modo que a força para aproximação das extremidades da traquéia foi uniformemente de 300gf. Após 30 dias de observação os animais foram tratados com dose letal de anestésico e KCl, quando foi ressecada a traquéia para medida dos diâmetros internos da anastomose e da traquéia normal, com auxílio de paquímetro digital. Na análise histopatológica com as colorações HE e tricrômico de Masson utilizou-se sistema digitalizado para quantificar as estruturas dos tecidos em cicatrização. Resultados: Foi observado maior índice de estenose da traquéia no grupo A que não utilizou corticóide, do que no grupo B, com diferença significante (p<0,01). A reação inflamatória, formação de fibras colágenas e de fibroblastos ocorreu com densidade média mais intensa no grupo A, caracterizando uma diferença significante (p<0,01). Conclusão: Os dados permitem concluir que o uso da metilprednisolona em cães submetidos a ressecção de traquéia e anastomose sob tensão contribuiu para diminuir a intensidade e frequência da estenose na zona da anastomose e fez reduzir a reação inflamatória nos tecidos em cicatrização.Artigo Influence of laparoscopy and laparotomy on gasometry, leukocytes and cytokines in a rat abdominal sepsis model(2006) Araújo Filho, Irami; Honorato Sobrinho, Abraão Allen; Rego, Amália Cinthia Meneses do; Garcia, Ana Claudia M. de Amorim; Fernandes, Daniele Pimentel; Cruz, Thaís Medeiros; Costa, Ticiana Cabral da; Medeiros, Aldo CunhaArtigo Influence of Splenectomy on the Biodistribution of Technetium-99m Dimercaptosuccinic Acid (99mTc-DMSA) in Rats(2008) Açucena, Maria Kadja Meneses Torres; Pereira, Kércia Regina Santos Gomes; Villarim Neto, Arthur; Rêgo, Amália Cínthia Meneses; Bernardo Filho, Mário; Azevedo, Ítalo Medeiros; Araújo Filho, Irami; Medeiros, Aldo CunhaArtigo Metabolic and hematologic consequences of colectomy associated to hepatectomy in rats(2011) Carvalho, Marília Daniela Ferreira; Araújo Filho, Irami; Azevedo, Ítalo Medeiros; Rêgo, Amália Cínthia Meneses; Medeiros, Aldo CunhaArtigo Oxacillin magnetically targeted for the treatment of Methicillin-Resistant S. aureus infection in rats(Acta Cirúrgica Brasileira, 2017-01) Carriço, Artur da Silva; Carvalho, Juliana Fernandes; Azevedo, Ítalo Medeiros; Rocha, Keyla Borges Ferreira; Medeiros, Aldo CunhaPurpose: To evaluate the effect of oxacillin bonded to magnetic nanoparticles in local infection model in rat. Methods: Twelve Wistar rats weighing 290±18g were randomly divided into four groups (n=6, each) and all rats had a magnet ring sutured on their right thighs. In the biodistribution group rats 0.1mL of 99mTc-magnetite (0.66 MBq) was injected i.v and after 30 minutes, biodistribution of 99mTc-magnetite was evaluated in right and left thighs. The other groups were inoculated with MRSA in each thigh muscles. Group 1 rats were injected i.v. with magnetite, group 2 with Magnetite + Oxacillin, group 3 with saline twice a day. After 24 hours samples of muscle secretion were harvested for microbiological analysis; muscle, lungs and kidneys for histology. Results: 99mTc-magnetite uptake was three-fold higher in right thigh muscles (with external magnet) than in the left. In magnetite and oxacillin-magnetite groups, bacterial/CFU was significantly lower in thigh muscles than in saline-controls. The inflammatory reaction in muscles and lungs was significantly lower in oxacillin-magnetite group-rats than in other groups (p<0.001) . Conclusion: This study confirms the potential antimicrobial activity of magnetic nanoparticles for Methicillin-Resistant S. aureus strains, which in addition to concentrate the antibiotic at the infection site, positively influenced the treatment.