Navegando por Autor "Guedes, Felipe Leite"
Agora exibindo 1 - 4 de 4
- Resultados por página
- Opções de Ordenação
Artigo Antibrush border antibody disease: a case report and literature review(Elsevier, 2021) Almeida, Jose Bruno de; Brito, Laíse Pereira Arcoverde Fechine; Guedes, Felipe Leite; Vale, Pedro Henrique Cavalcante; Santos, Rivaldo Pereira; Martins, Sílvia Queiroz Santos; Dantas, Gleiko Yuri de Figueredo; Wanderley, David; Araújo, Stanley de Almeida; Silva, Gyl Eanes BarrosAnti-brush border antibody (ABBA) disease, also called anti–low-density lipoprotein receptor-related protein 2 (anti-LRP2) nephropathy, occurs due to the formation of antibodies against brush border antigens of the renal proximal convoluted tubule. We report a case of ABBA disease in a male farmer in his 30s who presented with 2 years of polyuria, dysuria, nocturia, and urinary urgency. He described a history of long-term occupational exposure to pesticides and silica, evolving into possible pneumoconiosis, and prior pulmonary tuberculosis. At presentation, he had reduced kidney function (serum creatinine 3.6 mg/dL) with hyponatremia, hypokalemia, hypophosphatemia, a normal anion gap, metabolic acidosis, and respiratory acidosis, and 2.2 g/day of urine proteinuria. The kidney biopsy was consistent with ABBA, showing amorphous immune-deposits in the tubular basement membrane and strong positivity on indirect immunofluorescence in the brush border of the proximal tubules. The trigger for production of ABBA is still unknown, but it may be associated with chronic conditions such as pulmonary tuberculosis and occupational exposures such as silica and pesticides, as seen in the patient in this report. Most cases do not respond to immunosuppression, and the prognosis is poor.Artigo Collapsing glomerulopathy: a review by the collapsing brazilian consortium(Frontiers in medicine, 2022) Almeida, Jose Bruno de; Cutrim, Érico Murilo Monteiro; Neves, Precil Diego Miranda de Meneses; Campos, Marcos Adriano Garcia; Wanderley, Davi Campos; Teixeira Júnior, Antonio Augusto Lima; Muniz, Monique Pereira Rêgo; Ladchumananandasivam, Francisco Rasiah; Gomes, Orlando Vieira; Vasco, Rafael Fernandes Vanderlei; Brito, Dyego José de Araújo; Lages, Joyce Santos; Salgado-Filho, Natalino; Guedes, Felipe Leite; Magalhães, Marcelo; Araújo, Stanley de Almeida; Silva, Gyl Eanes BarrosCollapsing glomerulopathy (CG) is a clinicopathologic entity characterized by segmentar or global collapse of the glomerulus and hypertrophy and hyperplasia of podocytes. The Columbia classification of 2004 classified CG as a histological subtype of focal segmental glomerulosclerosis (FSGS). A growing number of studies have demonstrated a high prevalence of CG in many countries, especially among populations with a higher proportion of people with African descent. The present study is a narrative review of articles extracted from PubMed, Medline, and Scielo databases from September 1, 2020 to December 31, 2021. We have focused on populational studies (specially cross-sectional and cohort articles). CG is defined as a podocytopathy with a distinct pathogenesis characterized by strong podocyte proliferative activity. The most significant risk factors for CG include APOL1 gene mutations and infections with human immunodeficiency virus and severe acute respiratory syndrome coronavirus 2. CG typically presents with more severe symptoms and greater renal damage. The prognosis is notably worse than that of other FSGS subtypesDissertação Construção de um Atlas online de Patologia Renal para apoiar o ensino das glomerulopatias(Universidade Federal do Rio Grande do Norte, 2021-09-02) Guedes, Felipe Leite; Diniz Júnior, José; Rodrigues, Anna Giselle Câmara Dantas Ribeiro; 05661747403; http://lattes.cnpq.br/4440595486888973; http://lattes.cnpq.br/7913193754933633; http://lattes.cnpq.br/5855332665298988; Pereira, Edna Regina Silva; http://lattes.cnpq.br/4503589425013098; Salvador, Petala Tuani Cândido de Oliveira; http://lattes.cnpq.br/5628089389342234OBJETIVO: O objetivo do projeto é construir um Atlas online de Patologia Renal para apoiar o ensino das glomerulopatias na Residência Médica. METODOLOGIA: Tratase de um estudo de natureza descritiva, no qual a construção do Atlas online foi baseada no modelo de design instrucional ADDIE (Análise, Design, Desenvolvimento, Implementação e Avaliação). Essa descrição incluiu a avaliação da estratégia de ensino, que foi realizada através de uma pesquisa qualitativa, onde oito médicos residentes do Hospital Universitário Onofre Lopes, que utilizaram o Atlas por um intervalo de quinze dias, puderam emitir opiniões sobre o processo de ensinoaprendizagem através de um grupo focal. Por fim, foi realizada uma análise temática do material obtido por gravação de voz. RESULTADOS: A estratégia de ensino foi desenvolvida e publicada no formato de website. Esse produto possui três seções, dois módulos de conteúdo, 06 capítulos, 214 slides, 43 imagens explicadas, 04 provas contendo 10 quesitos cada, além de casos clínicos, perguntas de direcionamento, discussões clínicas e referenciais teóricos. A avaliação dos residentes evidenciou que a experiência ensino-aprendizagem foi favorável a complementar a lacuna de conhecimento da Patologia Renal, apresentou pontos positivos relacionados ao uso do recurso tecnológico em sua forma de apresentação. Além disso, houve espaço para a exposição das mudanças sugeridas pelo grupo de residentes. CONCLUSÕES: O projeto pode ser ampliado utilizando as colaborações obtidas através do grupo focal. Tecnologias educacionais semelhantes ao NefroAtlas podem ser inseridas através do Ensino Híbrido para complementar o aprendizado dos campos de prática da Residência Médica, tendo potencial para serem inclusas na Graduação.Artigo Translumbar hemodialysis long-term catheters: an alternative for vascular access failure(Brazilian Journal Of Nephrology, 2019-01) Moura, Fernando; Guedes, Felipe Leite; Dantas, Yuri; Maia, Ana Helena; Oliveira, Rodrigo Azevedo de; Silva, Artur Quintiliano Bezerra daIntroduction: Vascular access (VA) in hemodialysis (HD) is essential to end-stage renal disease (ESRD) patients survival. Unfortunately, after some years in HD program, a significant number of patients may develop VA failure for many reasons. In this situation, arterial venous fistula (AVF) confection or catheters placement in traditional vascular sites (jugular, femoral or subclavian) are not feasible. In this scenario, translumbar tunneled dialysis catheter (TLDC) may be a salvage option. Objectives: To describe placement technic, complications, and patency of 12 TLDC. Methods: A retrospective study was performed to analyze 12 TLDC placement in an angiography suite using fluoroscopic guidance at the University Hospital of the Rio Grande do Norte Federal University from January 2016 to October 2017. The data collected of the total procedures performed consisted of demographic characteristics, success rates, observed complications, patient survival, and catheter patency. Results: All 12 TLDC were placed with success; there were only 2 significant periprocedure complications (major bleeding and extubation failure); 41.6% of patients presented a catheter-related first infection after 98 ± 72.1 (6-201) days, but catheter withdrawal was not necessary, mean total access patency was 315.5 (range 65 - 631) catheter-days, and catheter patency at 3, 6 and 12 months was 91 %, 75%, and 45%. Conclusion: TLDC is an option for patients with VA failure, improving survival and acting as a bridge for renal transplantation.