Navegando por Autor "Barsottini, Orlando Graziani Povoas"
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Artigo ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome(Elsevier, 2020-11-03) Godeiro Junior, Clécio de Oliveira; Pessoa Neto, Agábio Diógenes; Aquino, Bárbara Cristina Vieira de; Brito, Paulo Santiago de Morais; Silva, Rodrigo de Alencar e; Moreira Neto, Manuel; Barsottini, Orlando Graziani Povoas; Dutra, Lívia Almeida; 0000-0002-4312-1633Anti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Limbic encephalitis (LE) is the most common manifestation. Anti-Ma2 LE can also be manifested as a pure psychiatric disturbance associated or not with hypokinesia. Other patients exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, due to diencephalic and/or upper brainstem involvement. These cases are challenging and demand extensive work-up for differential diagnosis.