Navegando por Autor "Arrais, Nívia Maria Rodrigues"
Agora exibindo 1 - 3 de 3
- Resultados por página
- Opções de Ordenação
Artigo Association between brain morphology and electrophysiological features in Congenital Zika Virus Syndrome: a cross-sectional, observational study(Elsevier, 2020-08) Sequerra, Eduardo Bouth; Rocha, Antonio Jhones Lima da; Medeiros, Galtieri Otavio Cunha de; Moreira Neto, Manuel; Maia, Claudia Rodrigues Souza; Arrais, Nívia Maria Rodrigues; Bezerra, Mylena Taíse Azevedo Lima; Jeronimo, Selma Maria Bezerra; Barros Filho, Allan Kardec Duailibe; Sousa, Patrícia S; Melo, Aurea Nogueira de; Queiroz, Claudio Marcos Teixeira deBackground: Intrauterine infection with the Zika virus (ZIKV) has been connected to severe brain malformations, microcephaly, and abnormal electrophysiological activity. Methods: We describe the interictal electroencephalographic (EEG) recordings of 47 children born with ZIKV-derived microcephaly. EEGs were recorded in the first year of life and correlated with brain morphology. In 31 subjects, we tested the association between computed tomography (CT) findings and interictal epileptiform discharges (IED). In eighteen, CTs were used for correlating volumetric measurements of the brainstem, cerebellum, and prosencephalon with the rate of IED. Findings: Twenty-nine out of 47 (62%) subjects were diagnosed as having epilepsy. Those subjects presented epileptiform discharges, including unilateral interictal spikes (26/29, 90%), bilateral synchronous and asynchronous interictal spikes (21/29, 72%), and hypsarrhythmia (12/29, 41%). Interestingly, 58% of subjects with clinical epilepsy were born with rhombencephalon malformations, while none of the subjects without epilepsy showed macroscopic abnormalities in this region. The presence of rhombencephalon malformation was associated with epilepsy (odds ratio of 34; 95% CI: 2 - 654). Also, the presence of IED was associated with smaller brain volumes. Age-corrected total brain volume was inversely correlated with the rate of IED during sleep. Finally, 11 of 44 (25%) subjects presented sleep spindles. We observed an odds ratio of 0·25 (95% CI: 0·06 - 1·04) for having sleep spindles given the IED presence. Interpretation: The findings suggest that certain CT imaging features are associated with an increased likelihood of developing epilepsy, including higher rates of IED and impaired development of sleep spindles, in the first year of life of CZVS subjectsTCC Desencadeamento e progressão de perda auditiva na Síndrome Congênita do vírus Zika: relatos de casos(Universidade Federal do Rio Grande do Norte, 2019-12-09) Ferreira, Mirelly Danglês de Oliveira; Araújo, Fabiana Cristina Mendonça; Arrais, Nívia Maria Rodrigues; Balen, Sheila AndreoliOs bebês expostos ao vírus Zika durante o período gestacional apresentam indicador de risco para deficiência auditiva, sendo necessário o monitoramento auditivo e nos de “falha” na Triagem Auditiva Neonatal (TAN) o diagnóstico audiológico. Logo, o presente estudo teve por objetivo caracterizar os achados audiológicos de dois pacientes com exposição ao vírus Zika, descrevendo quanto ao tipo, grau e configuração audiométrica, bem como caracterizar o quadro audiológico quanto ao desencadeamento e progressão de perdas auditivas na exposição ao vírus Zika, comparando os resultados audiológicos nos primeiros 4 anos de vida. A amostra foi composta por duas crianças atendidas no projeto ouvir no período de 2015 a novembro de 2019, tendo realizada anamnese para obter informações a respeito do período pré, peri e pós-natal e, posteriormente, a inspeção do meato acústico externo, a fim de verificar se havia condições para dar continuidade aos seguintes procedimentos: triagem auditiva, emissões otoacústicas por estímulo transiente e por produto de distorção, timpanometria, pesquisa dos reflexos acústicos, audiometria de reforço visual, potencial evocado auditivo de tronco encefálico clique e frequência específica por via aérea e via óssea. A partir dos achados foi verificado que as crianças deste estudo apresentaram desencadeamento e progressão de alterações auditivas. O S2 identificado com perda auditiva sensorioneural de grau leve e configuração ascendente à direita e U invertido à esquerda e o S1 com desencadeamento de alteração auditiva à direita e perda auditiva de grau leve e configuração audiométrica ascendente à esquerda.Artigo Development of infants presented with congenital syphilis in their first months of life(Revista Cefac, 2021) Balen, Sheila Andreoli; Silva, Thalinny da Costa; Santos, Leila Juliane Pinheiro do Nascimento; Arrais, Nívia Maria Rodrigues; https://orcid.org/0000-0003-1353-4362Purpose: to evaluate the cognitive, language, and motor development of infants with congenital syphilis in their first months of life. Methods: a sample of 52 infants, from 21 to 112 days of age, born in public maternity hospitals, divided into a study group of 28 infants with congenital syphilis and a control group 24 infants without risk indicators for hearing loss. They underwent the Neonatal Hearing Screening Protocol with automated Brainstem Auditory Evoked Potential. The research instrument was the Bayley-III Scale, consisting of the cognitive, language (receptive and expressive), and motor (fine and gross) subscales. The raw scores were entered into the software that accompanies the Bayley-III scale kit to calculate the scores (scaled and composite) and perform qualitative analysis. The Mann-Whitney test and the Wilcoxon test was applied and used a 5% significance level. Results: a similarity between groups for the demographic parameters, maternal education level, and socioeconomic level, was seen. There was no statistically significant difference between groups when comparing the cognitive, receptive language, expressive language, fine motor, and gross motor subscales. Conclusion: infants with congenital syphilis treated at birth have a cognitive, language, and motor development within that expected for their age group in their first months of life.